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Stability testing is a critical component of ensuring the quality, safety, and efficacy of small molecule pharmaceuticals. In this blog, we'll discuss the analytical techniques commonly used in stability testing and best practices for conducting these tests:
1. High-Performance Liquid Chromatography (HPLC)
HPLC is a widely used analytical technique for stability testing due to its ability to separate and quantify drug substances and degradation products with high precision and sensitivity. HPLC methods can be developed to analyze a wide range of compounds, making them suitable for assessing the stability of various pharmaceutical formulations.
2. Gas Chromatography (GC)
GC is commonly employed for stability testing of volatile compounds and degradation products. GC separates volatile compounds based on their affinity for the stationary phase and their volatility, making it suit
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Risk-Based Approach: CDMOs adopt a risk-based approach to identify and prioritize critical quality attributes (CQAs) and process parameters that can impact the quality, safety, and efficacy of investigational products. By conducting risk assessments and leveraging scientific knowledge and prior experience, CDMOs identify potential risks and implement control strategies to mitigate risks and ensure product quality
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Efficiency is paramount in drug product manufacturing, as it directly impacts production costs, time-to-market, and overall competitiveness in the pharmaceutical industry. Contract Development and Manufacturing Organizations (CDMOs) play a critical role in maximizing efficiency through process optimization strategies that streamline operations, reduce waste, and enhance productivity.
Technology transfers play a crucial role in process optimization by facilitating the seamless transfer of manufacturing processes, know-how, and best practices from clients to CDMOs. By collaborating closely during technology transfers, CDMOs can implement process optimization initiatives more effectively and deliver value-added solutions to their clients.
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https://renejix.com/drug-product-manufacturing/technology-transfers/In the competitive pharmaceutical landscape, selecting the right PCD company is pivotal for success. Crystomed stands out as the premier choice, earning its reputation as the leading General Range PCD Company in India. Here's why teaming up with Crystomed can be your ticket to a thriving pharmaceutical business:
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Diverse Product Portfolio: Crystomed offers a varied selection of high-quality pharmaceutical products in the General Range, addressing a broad spectrum of healthcare needs.
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https://www.crystomed.com/general-range-pcd-company/Key pharmaceutical companies, having successfully concluded clinical trials, are gearing up for potential new product launches. Analysts express optimism about the imminent expansion of the growth horizon within the Dengue vaccine industry. The strategic insights provided by FMI underscore the industry’s potential to address the rising prevalence of dengue fever, particularly in the Asia-Pacific region.
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Rand Paul demands Fauci, NIH scientists disclose pharmaceutical royalties
Sen. Rand Paul has introduced a bill that would force federal employees to disclose royalties they receive from new medical innovations.
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Everything from chemotherapy and attention-deficit hyperactivity disorder (ADHD) drugs to weight loss medications and everything in between is currently in short supply due to lingering supply chain problems stemming from the Wuhan coronavirus (COVID-19) "pandemic."
"Drug shortages are affecting many areas of pharmacy practice, such as retail, compounding and hospitals," said Anthony Longo, a doctor of pharmacy and director of pharmacy at Northwell Long Island Jewish Forest Hills in Queens, New York.
In nine out of 10 cases, surveyed technicians indicated that they offer substitute drugs whenever possible, though nearly half of the time, around 45 percen
Drug shortages reported at 96% of U.S. pharmacies as Big Pharma’s supply chain begins to fail – NaturalNews.com
The Pharmacy Technician Certification Board (PTCB) conducted a survey recently which found that 96 percent of pharmacy technicians across the country are reporting shortages of what are considered “essential” pharmaceutical drugs. Everything from chemotherapy and attention-deficit hypera..
https://www.naturalnews.com/2023-09-26-drug-shortages-96-percent-pharmacies-supply-chain.htmlThe Omicron offshoot carries more than 35 mutations in key portions of the virus compared with XBB.1.5, the dominant variant through most of 2023 - a number roughly on par with the Omicron variant that caused record infections compared to its predecessor."
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A Massachusetts blast site that killed one pharmaceutical plant worker is moving to the cleanup phase. The explosion tore the roof off a building and killed one worker.
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Some of the world's leading makers of flu vaccines say they could make hundreds of millions of bird flu shots for humans within months if a new strain of avian influenza ever jumps across the species divide.
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"Western governments, non-governmental organizations, transnational organizations, pharmaceutical corporations, media, and financial corporations have cooperated via public-private partnerships, which I assert is a euphemism for fascism, to deploy the most massive, globally harmonized, psychological propaganda operation in the history of the world."
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The global peptide synthesis market size reached USD 506.2 Million in 2021 and is expected to register a revenue CAGR of 7.2% during the forecast period, according to the latest analysis by Emergen Research. Peptide synthesis market revenue growth is driven by factors such as increasing use of peptides in pharmaceutical drugs, development of personalized medicine, increase in research activities & availability of fundi
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